The Maine Science Assessment is administered in grades 5, 8, and 3rd year of high school. Students with the most significant cognitive disabilities may qualify for MSAA Science, Maine's alternate assessment for science.

Maine Science
The Maine Science Assessment is based on the Maine Science and Engineering Standards, for which the Next Generation Science Standards serves as the foundation. The assessment focuses on performance expectation levels based on three-dimensional learning that incorporates science practices and crosscutting concepts with disciplinary core ideas.

MSAA Science
The MSAA Science is Maine’s alternate assessment for science. This assessment is administered in grades 5, 8 and 3rd year of high school and is designed for students with the most significant cognitive disabilities. The assessment is based on the alternate achievement standards in science, the Extended Performance Expectations [EPEs], which are aligned to the Next Generation Science Standards.