St. Andre's Roman Catholic parish is a complex containing five buildings (church, school, convent, rectory and garage) located just southeast of downtown Biddeford. Erected starting in 1900, three of the four principal buildings - the rectory, convent and church - contribute to the significance of the historic district. Stylistically the church is Romanesque, the rectory is Second Empire-style and the convent and (non-contributing ) former school were built in the Colonial Revival Style. St. Andre's parish is significant in the area of Ethnic Heritage for its association with the French-Canadian community in Biddeford. The complex is also significant under in the area of Architecture as a collection of well-designed early 20th century buildings that collectively form a noteworthy example of a Roman Catholic parish complex. The church is also important as a local example of the work of Boston architects Chickering & O'Connell, representing an important component of the firm's work. The period of significance for the parish runs from 1900, the date of earliest construction, to 1965, the National Park Service 50-year cut-off date for National Register listing.