Christopher W. Babbidge (D-Kennebunk) - Retiring from the Legislature (withdrew after primary)
Christopher R. Barstow (D-Gorham) - Retiring from the Legislature (withdrew after primary)
*Patricia A. Blanchette (D-Bangor) - Retiring from the Legislature
*Lawrence Bliss (D-South Portland) - Running for State Senate
John R. Brautigam (D-Falmouth) - Retiring from the Legislature
Richard John Burns (D-Berwick) - Running for State Senate
*Marilyn E. Canavan (D-Waterville) - Retiring from the Legislature
Jill M. Conover (D-Oakland) - Retiring from the Legislature
Margaret M. Craven (D-Lewiston) - Running for State Senate
*Glenn Cummings (D-Portland) - Retiring from the Legislature
Michael E. Dunn (D-Bangor) - Retiring from the Legislature
Sean Faircloth (D-Bangor) - Retiring from the Legislature
David W. Farrington (D-Gorham) - Retiring from the Legislature
Jeremy R. Fischer (D-Presque Isle) - Retiring from the Legislature (withdrew after primary)
Charles D. Fisher (D-Brewer) - Retiring from the Legislature
*Stan Gerzofsky (D-Brunswick) - Running for State Senate
Carol A. Grose (D-Woolwich) - Retiring from the Legislature
Troy Dale Jackson (D-Allagash) - Running for State Senate
*Theodore S. Koffman (D-Bar Harbor) - Retiring from the Legislature
*Jacqueline A. Lundeen (D-Mars Hill) - Running for State Senate
Elaine Makas (D-Lewiston) - Running for State Senate (lost in primary)
*Boyd P. Marley (D-Portland) - Retiring from the Legislature
David Miramant (D-Camden) - Running for State Senate
*Jacqueline R. Norton (D-Bangor) - Retiring from the Legislature
*John L. Patrick (D-Rumford) - Retiring from the Legislature
*Raymond G. Pineau (D-Jay) - Retiring from the Legislature
Anne M. Rand (D-Portland) - Running for State Senate (lost in primary)
*Peter L. Rines (D-Wiscasset) - Running for State Senate
Mark Paul Samson (D-Auburn) - Retiring from the Legislature
Kimberly E. W. Silsby (D-Augusta) - Retiring from the Legislature (withdrew after primary)
*Deborah L. Simpson (D-Auburn) - Running for State Senate
Lance Weddell (D-Frankfort) - Retiring from the Legislature
*James D. Annis (R-Dover-Foxcroft) - Retiring from the Legislature
Robert A. Berube (R-Lisbon) - Retiring from the Legislature
Robert H. Crosthwaite (R-Ellsworth) - Retiring from the Legislature
*Brian M. Duprey (R-Hampden) - Retiring from the Legislature
Harold Ian Emery (R-Cutler) - Retiring from the Legislature
Lawrence E. Jacobsen (R-Waterboro) - Retiring from the Legislature
Scott E. Lansley (R-Sabattus) - Retiring from the Legislature
Roberta M. Muse (R-Fryeburg) - Retiring from the Legislature
Christopher W. Rector (R-Thomaston) - Running for State Senate
David Gilman Savage (R-Falmouth) - Retiring from the Legislature (withdrew after primary)
Joseph L. Tibbetts (R-Columbia) - Retiring from the Legislature
Richard G. Woodbury (U-Yarmouth) - Retiring from the Legislature