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Raising the Bar for Patient Outcomes Mixed Episodes in Bipolar Disorder:
Trapped Between Two Worlds
12/8/2004

Event Description:
The redefinition and expansion of bipolar disorder to include a broad spectrum of manic states and dysphoric symptoms has dramatically increased prevalence rates from 1% (previous estimate) to around 5%. Over 40% of all bipolar episodes are mixed states. Furthermore, by some estimates, 30-55% of all major depression lies along the bipolar spectrum. Bipolar II is characterized by hypomania and episodes of depression. Bipolar III refers to antidepressant-associated hypomania. Mixed states and dysphoric symptoms may be clinically challenging to characterize, resulting in significant diagnosis and treatment delays. Atypical depressive symptoms, anxiety states, and comorbid illness (including substance/alcohol abuse) may further confound diagnosis and treatment. In this evidence-based psychCME TV activity, experts will discuss how to recognize the entire clinical spectrum of bipolarity in order to maximize diagnostic accuracy, treatment efficiency, and thus patient outcomes.

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